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Colchicine works but it takes 4 or 5 days and causes diarrhea in treatment sized doses.
Information about Colchicine.
Before using this medicationtell your doctor or pharmacist your medical historyespecially ofkidney problemsliver problemssuch as cirrhosis
The most common side effects of colchicine capsules include abdominal paindiarrheanauseaand vomiting.
Alcohol can decrease this drug’s effectivenessLimit alcohol while taking this drug.
Co-administration of colchicine capsules with propafenonea P-gp inhibitorat 225 mg BID for 5 daysin a pharmacokinetic study in healthy volunteersdid not cause any changes in systemic levels of colchicineThis indicates that propafenone can be administered with colchicine capsules without any dose adjustmentHoweverthese results should not be extrapolated to other P-gp inhibitors as colchicine is known to be a substrate for P-gp and case reports of colchicine toxicity associated with the co-administration of P-gp inhibitors such as cyclosporine have been published.
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